BVMO-catalysed dynamic kinetic resolution of racemic benzyl ketones in the presence of anion exchange resins.
نویسندگان
چکیده
4-Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB was employed in the presence of a weak anion exchange resin to perform dynamic kinetic resolutions of racemic benzyl ketones with high conversions and good optical purities. Different parameters that affect to the efficiency of the enzymatic Baeyer-Villiger oxidation and racemisation were analyzed in order to optimize the activity and selectivity of the biocatalytic system.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 8 5 شماره
صفحات -
تاریخ انتشار 2010